Alfardan established the Alfardan Group in 1954. It expanded to include Alfardan Hospitality in 2006. Its hotels include the Marsa Malaz Kempinski, the Pearl-Doha, Kempinski Residences & Suites Doha, the St. Regis Doha, and the St. Regis Al Mouj Muscat. Alfardan also founded the Commercial Bank of Qatar, where he is the vice chairman, and he is the first deputy to the chairman at the Qatar Businessmen Association.