Al-Khateeb assumed her role as CEO of KNPC in November 2022, where she oversees 6,270 employees. The company recorded total revenues of $33.8 billion for the fiscal year that ended in March 2022. Al-Khateeb has 28 years of experience in the oil sector. She previously established the Worker Woman Committee in the Oil and Petrochemical Industries Workers Confederation. She also led the registration of the Flare Gas Recovery Unit—the first Kuwaiti project to be listed in the United Nations Framework Convention on Climate Change. Al-Khateeb is also a chairperson and board member for the Kuwait Paraxylene Production Company and a member of the Kuwait Women Cultural & Social Society, among other roles. Before taking her current position, she was deputy CEO at the Mina Abdullah Refinery.