Having first joined KIPCO in 1997 as a general manager, Al Sabah assumed her current role in January 2022. In November 2022, KIPCO completed its merger with one of its portfolio companies, Qurain Petrochemical Industries, which created one of the largest public companies in the region with a market cap of $1.8 billion as of January 4, 2023. Al Sabah also helped establish the American University of Kuwait and the United Education Company in 2003. She now sits on the boards of the Gulf Insurance Group, OSN, Kamco Invest, and KIPCO, as well as chairing the board of trustees for AUK and the board of directors for UEC.