Al Shamisi became the Managing Director and Group CEO of AD Ports Group in 2019 after joining the company in 2008. In November 2023, AD Ports Group made a $200 million investment into 10 vessels, which are expected to arrive in Q4 2023. Al Shamisi is also the chairman of Aramex, ADNEC, the KEZAD Group board of directors, and the Arab Sea Port Federation. He is the Vice Chairman of the Board of the UAE Sailing & Rowing Federation and a board member of the Make-A-Wish Foundation U.A.E.