Mansour launched her namesake fashion brand in Beirut in 2010. The fashion house is known for its intricate ready-to-wear line and bespoke bridal wear. In 2023, Mansour collaborated with 111SKIN and Fashion Trust Arabia, introducing a limited-edition Eye Lift Edit. In 2024, Mansour became a founding member of Dubai Fashion Week. Mansour’s designs have been seen on celebrities, including Gigi Hadid, Sarah Jessica Parker, Alexandra De Hanovre, and Lady Gaga. Mansour’s label had over 232,000 followers on Instagram as of June 2024.