Kadi launched his fashion house in Beirut in 2011. In 2020, Kadi was designated a UNEP regional goodwill ambassador for a sustainable fashion program in West Asia. Among the celebrities who have worn Kadi designs are Beyoncé, Salma Hayek, Hend Sabri, Najwa Karam, Aishwarya Rai, Mrmr, Dima Kandalaft, and Stephanie Atala. The brand had a million followers on Instagram as of June 2024. In 2022, Maison Rami Kadi launched its first Spring-Summer 2022 NFT collection, “Lucid Algorithms,” on the Cardano blockchain.