Almeshekah founded Outliers Venture Capital in 2019 to invest in fintech, digital commerce, and cybersecurity. As of June 2024, it had 19 companies in its portfolio. Its startups include MENA-based Lean Technologies, Tabby, Soum, Breadfast, and U.S.-based Normalyze, Matter, and StrikeReady. Almeshekah is a board member at Lean Technologies, Penny Software, ALHOKAMA Eye Center, and Sonet.io, and an advisory board member at the Saudi Ministry of Municipalities and Housing.