Khelif clinched a gold medal in the women's 66kg category at the Paris 2024 Olympics. She was also the first female Algerian boxer to win a world championship medal after attaining a silver medal at the 2022 World Championships. She competed at Tokyo 2020, where she became the first female boxer to represent Algeria at the Olympics. She has won gold at the 2022 Mediterranean Games, the 2022 African Championships, and the 2023 Arab Games. In December 2023, Khelif was also appointed as a UNICEF ambassador to Algeria for two years (2024-2025).