Kaddoumi joined Medtronic in 2012 as VP and managing director for the Middle East and Africa and assumed his current role in July 2024, leading over 10,000 people. In 2023, Medtronic trained over 38,000 healthcare professionals and key opinion leaders in the region and treated 500,000 additional patients. Kaddoumi sits on the boards of Kcrew, Xwell, THB Global, and Kidzonet. Before joining Medtronic, Kaddoumi was the country general manager for Saudi Arabia at GE Healthcare.