El Hamamsy has led ODE and its parent company, Orascom Development Holding since 2020. In Q1 2024, ODH's new real estate sales increased by 143% to $290 million and revenues by 16% to $173 million. As of May 2024, ODH had a land bank of over 100 million square meters in Europe, the Middle East, and North Africa, with a hospitality portfolio including 33 hotels with over 7,000 rooms. El Hamamsy previously spent 18 years at McKinsey & Company.