Mahfouz assumed her current role in 2014. In February 2024, Al-Tijari announced a partnership with Network International to aid its ongoing digital transformation, including fraud detection and prevention, tokenization, and cardholder self-serve application. In the first nine months of 2024, the bank had $15.2 billion in assets and recorded net profits of $290.6 million. Mahfouz has held multiple senior executive positions at Al-Tijari since joining the bank in 2000, including general manager in its New York branch.